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L-glutathione and L-cysteine may brighten skin and dark spots

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doi: 10.3389/fmed.2026.1761721 Received 09 December 2025 Revised 12 January 2026 Accepted 26 January 2026 Published 20 February 2026 Volume 13 - 2026 Edited by Constantin Caruntu, Carol Davila University of Medicine and Pharmacy, Romania Reviewed by Mahmood Ahmed, University of Education Lahore, Pakistan Mohammad Amin Raeisi Estabragh, Kerman Medical University, Iran Updates Copyright 2026 Sanlier, Sacinti, Turkoglu and Sanlier

However, in pathological states such as BPD and other lung injuries, mitochondrial fragmentation increases, and membrane depolarization induces PINK1 accumulation at the outer mitochondrial membrane, which recruits and activates Parkin

Reduces oxidative stress Oxidative stress diabetes cancer rheumatoid arthritis Glutathione is May improve psoriasis A 2022 review notes that treatments that increase antioxidants like glutathione can help manage oxidative stress and the reactive oxygen species (ROS) that are related to it