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Further studies revealed that mechanistic studies confirmed that DHODH could only perform its ferroptosis inhibitory function when localized in mitochondria and that this function was dependent on its enzymatic activity

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Conclusion and future perspectives MASLD has a globally increasing prevalence with the potential to progress to its more severe form, MASH, and is an independent risk factor for cardiometabolic disorders

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doi: 10.3390/molecules28030982 82 Hyun-OhLJi-WeonCJeong-HoBJae-HyeonOSang-ChoonLChang-KugK

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