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Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)

Colony-forming units (CFUs) were recorded after overnight incubation at 37 C

Jiang X, Zhou Y, Sun AJ, Xue JL

Similarly, rats harboring the same DMT1 G185R mutation show reduced susceptibility to 6-hydroxydopamine (6-OHDA)-induced neurotoxicity, with 42.6% dopaminergic neuron loss versus 61.6% in wild-type and 65.9% in heterozygous animals ( Lysosomes serve as dynamic iron reservoirs and key regulators of cellular iron homeostasis

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