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Tophi develop in and around the joints leading to joint destruction and chronic (long-term, continuous) joint pain and stiffness

Due to their generally lower incidence of adverse effects, these natural compounds are considered promising and safer alternatives to conventional chemotherapeutic agents [18]

N-acetylcysteine, or NAC, is a modified version of L-cysteine

The AuNP coating provides a favorable interface for stable aptamer immobilization through thiol-based self-assembled monolayers, while also enhancing conductivity and effective surface area, both of which contribute to improved signal quality

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