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Description

Sikiric et al., 1997a

DNA double-helix binds regulatory peptides similarly to transcription factors.Neuroendocrinology Letters, 26(3), 237-241

Appetite and Food Intake Reduction Moderate Research Cagrilintide acts on brain regions involved in hedonic appetite regulation, complementing the homeostatic appetite suppression provided by GLP-1 receptor agonists

This creates an extraordinarily high binding affinity with pK = 16.44, approximately 10 million times higher than other tripeptides and comparable to albumins copper binding (pK = 16.2)