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Jori C, Chaudhary AA, Rashid S et al (2023) Biomaterial-based strategies for immunomodulation in IBD: current and future scenarios

doi: 10.1111/bpa.12763 115 GuneykayaD.IvanovA.HernandezD

Measuring total alpha-synuclein is also unlikely to reflect disease status, as the smaller oligomeric species are thought to be the most damaging forms

It is a natural carrier of sulfur, which gives it antioxidant and detoxifying properties

The rate-limiting enzyme in this pathway is Indoleamine 2,3-dioxygenase 1 (IDO-1), which is upregulated by pro-inflammatory agents such as interferon- (IFN-) and tumor necrosis factor-alpha (TNF-), interleukin-1 (IL-1), interleukin-12 (IL-12), all cytokines that are released during inflammatory responses (Yang et al., 2024)