mitochondrial glutathione regulation and functions Pleiotropic effects of a mitochondrion-targeted reductase inhibitor on restraining tumor cells glutathione mitochondrial density Glutathione: Recent

Aptamers are thermostable and chemically stable, and chemical modification can enable their conjugation to nanoparticles, drugs, or other nucleic acid drugs to improve cellular uptake

Studies have shown that GSTP1 plays a crucial role in maintaining cellular oxidative homeostasis and regulating cell proliferation and apoptosis (Tew et al., 2011)

Therefore, methionine is converted into methionine sulfoxide which is then reconverted to the methionine throughout the oxidation of NADPH (Atmaca 2004

All MD simulations were performed with the program package GROMACS (version 2020.4) 32 using the GROMOS 54a7 force field 33

In sum, emodin emerges as a multi-dimensional agent that aligns a range of cell death pathways (necroptosis, autophagy, and ferroptosis) with immune reprogramming to thwart tumor progression and metastasis