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Induced/reduced peaks were determined by overlapping peaksets with bedtools intersect 108 , after which gene TSSs overlapping peaks (100 kb, +50 kb) were determined with bedtools closest 108 , and motif enrichment was obtained with findMotifsGenome.pl script from the HOMER v5.1 package 110

Santofimia-Castao P, Garcia-Sanchez L, Ruy DC, Sanchez-Correa B, Fernandez-Bermejo M, Tarazona R, Salido GM, Gonzalez A (2015b) Melatonin induces calcium mobilization and influences cell proliferation independently of MT1/MT2 receptor activation in rat pancreatic stellate cells

These mixed responses cannot be generalized, but the fact that a subset experience real improvement makes this an important signal to investigate

These multi-subunit enzyme complexes use lipoic arms covalently attached to their E2 subunits to transfer an acyl group to coenzyme A (CoA)

SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC