napqi and glutathione 5οΈβ£ Antidote: NAC (N-acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. π’ Example: Hospitals use NAC as the standard treatment for APAP overdose Fasting depletes Glutathione, turning "safe"
Fasting depletes Glutathione, turning "safe" Paracetamol doses into a liver toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. #MedEd # Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram Solved The following figure shows the metabolism of the First line treatment for acetaminophen overdose: A. Flumazenil B. Naloxone C. N acetylcysteine D. Sodium bicarbonate Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine YouTube
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