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Biochemistry Mosc 65:7576536 Harris RC, Marlin DJ, Dunnett M et al (1990) Muscle buffering capacity and dipeptide content in the Thoroughbred horse, Greyhound dog and man

However, preclinical studies have highlighted several critical safety concerns, particularly regarding cell retention, biodistribution, and oncogenic risk

An experimental analysis of a group of cancer cell lines with low and high GPX4 expression demonstrated that inhibiting DHODH could induce ferroptosis in tumor cells with low GPX4 expression while enhancing ferroptosis resistance in cancer cells with high GPX4 expression

doi: 10.1016/s0278-5846(96)00103-0