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Among them, NHEJ reassembles a broken DNA end under DNA-PKcs, while HR is a high fidelity repair mechanism activated by ATM activation (Williams et al., 2007

Beyond coupling to the TCA cycle, an essential function of the ETC is sustaining the activity of dihydroorotate dehydrogenase (DHODH), a key enzyme in de novo pyrimidine synthesis

Glucose transport families SLC5 and SLC50

The term lipotropic literally means fat-loving, referring to substances that have an affinity for lipids and assist in their breakdown

Mitochondrial function and respiration Isolated WAT mitochondria, cultured primary differentiated adipocytes and MEFs were assayed for OCR using a Seahorse XFe96 Extracellular Flux Analyzer (Agilent Technologies)