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Remember: it is always important to drink enough water to help flush everything out

SC: Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing review and editing

Some antihyperglycemic drugs, such as metformin, pioglitazone, and sitagliptin, have been found to induce macrophages to shift to the M2 phenotype (314, 315)

Recycled citrulline synergizes with aspartate to synthesize arginine for NOS reuse in turn by upregulating argininosuccinate synthase and argininosuccinate lyase in M1 macrophages through the citrullineNO cycle [58]