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Aging: a theory based on free radical and radiation chemistry

During sample collection an assessment as to whether an individual was affected with konzo was conducted following the WHOs 3 main criteria for diagnosis including evidence of (1) a visible symmetric spastic abnormality of gait while walking or running, (2) a history of onset of less than 1 week followed by a nonprogressive course in a formerly healthy person, and (3) bilaterally exaggerated knee or ankle jerks without signs of disease of the spine

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An important benefit of MRM is that when high-purity standards are available, the selective detection of specific precursorproduct ion pairs can enhance sensitivity and improve LOD

Consistently, another study reported that patients hospitalized with COVID-19 who avoided ICU admission had higher serum RvE3 levels, reinforcing the association between PRLMs abundance and disease severity [203]