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3) HNE inhibited inflammasome activation in mouse acute lung injury and sepsis models

However, a single enzyme, common to Schistosoma spp ., was identified to possess both GR and TrxR activities ( SCHEME 1 TGR from Schistosoma mansoni (SmTGR) is a homodimeric, flavin-dependent enzyme which can accept electrons from nicotinamide adenine dinucleotide phosphate (NADPH) and reduce both oxidized glutathione (GSSG) and thioredoxin (Trx ox ) (Scheme 1)

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10.1152/ajprenal.00422.2018 121 WeiW.YangL.WangB.TangL.LiJ.LiuC.et al (2025)

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