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Secondary analyses of these studies suggested that weight loss might be the main driver of GLP-1RA efficacy in MASH, supported by the lack of expression of GLP-1 receptors in the human liver 93

Patients were selected after treatment completion, introducing potential selection bias

In that situation, repeating the same treatment protocol may fail because peripheral nerve irritation, scar tissue, TMJ or muscle-related triggers, central sensitization, or another pain generator has not been identified

However, proper growth hormone therapy requires medical supervision to maximize benefits while minimizing risks

During this phase, the hair completely separates from the papilla and falls out, being "pushed out" by the newly growing anagen hair in the follicle