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In macrophages, this functional duality is especially important because lipin-1 can couple glycerolipid metabolism to inflammatory signaling while also supporting nonenzymatic programs linked to metabolic adaptation and pro-resolving function

Interventions that mildly activate HIF signaling such as intermittent hypoxia, exercise, and pharmacological stabilizers have demonstrated protective effects against aging-related degeneration, positioning HIF-hemoglobin pathways as promising targets in longevity research [10]

Moringa leaf extract increases tolerance to salt stress, promotes growth, increases yield, and reduces nitrate concentration in lettuce plants

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[21, 22, 23, 24] This notion was further supported by recent data from Muller et al