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Description

Synergetic Cholesterol-Lowering Effects of Main Alkaloids from Rhizoma Coptidis in HepG2 Cells and Hypercholesterolemia Hamsters

The organs typically affected are lungs, kidneys, liver, heart, brain, and gastrointestinal tract

These fatty acid substrates are oxidised non-enzymically by free radicals or through different enzymic pathways including the cyclo-oxygenases (COX), lipoxygenases (LOX) and cytochrome P450 pathways to produce both pro-inflammatory and resolving eicosanoids (Fig