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Several garlic-derived organosulfur compounds, including S-allylcysteine and ajoene, have been found to inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), a critical enzyme in the cholesterol biosynthesis pathway (39, 40)

Furthermore, the previous research about the correlation between the gut microbiota and the occurrence and development of IBS has been observed and the gut-brain axis plays a vital role, which was consistent with the hypothesis of PD originates in the gut (Braak et al., 2006

Depending on the nature of this final cleavage, the procedure can be modified to give a C-terminal acyl thiocyanate peptide product which automatically rearranges to a thiohydantoin incorporating the penultimate C-terminal unit

Bibcode:2000Sci...289.1567M

This momentum has been further propelled by advancements in next-generation sequencing (NGS) technologies (Singh 2024), which have accelerated the acquisition of genomic, transcriptomic, and metabolomic datasets