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Additionall chemical modifications at mutant Cys212, e.g

Some foods to consider include: Cruciferous Vegetables: Broccoli, cauliflower, and Brussels sprouts are great sources

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the pentamer was also excluded as a potential form of Ssp4 since it generated a large membrane disruption site incompatible with the experimental observations

Consistent with expectations, bona fide p53 targets including HDM2 and CDKN1A were among the most highly up-regulated genes in Control cells, whereas genes known to be negatively regulated by p53, such as E2F2 , were strongly down-regulated (el-Deiry et al, 1993