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High expression of GT is commonly found on cells involved in transport, on the luminal surface of secretory and absorptive cells

for example, the GPX4 gene becomes methylated following treatment of nucleus pulposus cells by HCys, resulting in lower levels of both GPX4 mRNA and protein [79]

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10.3390/cancers12082197 16 ChenY

For an experimental insight into the dynamic intracellular stabilization and translocation of Nrf2 in live cells, Nrf2, heme oxygenase 1 (HMOX1), and sulfiredoxin (SRXN1) monoclonal HepG2-based BAC-GFP reporter lines (Wink et al