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Dexamethasone, a synthetic glucocorticoid, has been documented to elicit the production of ROS either through direct means or as a consequence of endothelial nitric oxide synthase (eNOS) uncoupling, which is attributed to the constrained availability of tetrahydrofolate (59, 60)

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Hydroxyapatite, zirconia, carbonates of calcium, aragonite, quartz, TiO 2 , metal/metal oxides (M/MO), and bioactive mineral glass hybrids are examples of inorganic particles that are blended with CH-SFn (Sionkowska and Kozowska, 2010