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Personal physiology and underlying health status influence how someone may respond to such compounds.

Kaur et al., 2022), neurodegenerative diseases, such as Alzheimer (Traxler et al., 2022), and cardiovascular diseases (Tran and Wang, 2019)

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Serious and life-threatening cases of symptomatic bradycardia as well as one case of fatal cardiac arrest reported with coadministration of amiodarone with either Harvoni (ledipasvir and sofosbuvir fixed-dose combination) or with Sovaldi (sofosbuvir) in combination with another direct acting antiviral