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Type I collagen (Col ): promotes Col synthesis by 40% -50%, which accounts for 90% of the bone matrix and determines bone toughness and strength

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Zn deficiency can result in growth stunting, affecting the skin, gastrointestinal tissues, the immune system, the skeletal system, and the reproductive systems most severely (20)

455 Future research should elucidate how aberrant sensory afferent activity interacts with maladaptive CNS plasticity to initiate and sustain neuropathic pain