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The present study will investigate the reversal of long-term glutamine blockade-induced upregulation of PD-L1 in bladder cancer cells through combination therapy with JHU083 and gefitinib [105]

PMID: 26029106

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This interaction leads to mitochondrial abnormal function, elevated ROS generation, and triggers apoptosis through the activation of the p38 MAPK/c-jun N-terminal kinases (JNK) signaling cascade in cervical cancer cells [44]

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