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Marincola Smith, P, Tomita, K, Cass, SH, Hirata, Y, Pan, C, Shen, SE, Wang, X, Wang, XS, Williams, LA, Arvide, M, To, C, Rajaram, R, Rice, DC, Hofstetter, WL, Antonoff, MB, Mehran, RJ, Vaporciyan, AA, Walsh, GL, Maxwell, JE, Snyder, RA, Kim, M, Tzeng, CD, Badgwell, BD, Mansfield, PF, Katz, MH, Swisher, SG , Lee, JE, Ikoma, N

Recently, the existence of an M3 activation phenotype acquired by proliferative microglia in response to colony-stimulating factor-1 (CSF-1) and IL-34 has also been suggested (Walker and Lue, 2015)

The treatment of cobalamin-related remethylation disorders aims to reduce tHcy andin combined defectsto normalize MMA in order to improve clinical features [2]

After completing the treatment, the nude mice were euthanized 48 h later

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