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Under oxidative stress, certain cysteine residues on KEAP1 undergo chemical modifications that decrease NRF2 binding affinity, thus facilitating the expression of protective redox-related genes [89]

The large heterogeneity for some outcomes, such as CAD, may suggest different mechanisms underlying the genetic associations or the existence of pleiotropy [37]

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Ammonium under solution culture alleviates aluminum toxicity in rice and reduces aluminum accumulation in roots compared with nitrate

A meta-analysis of adult studies on AIH showed poor sensitivity (ANA: 65%, ASMA: 59.3%) and reasonably good specificity (ANA: 75.1%, ASMA: 92.6%) of ANA and ASMA for the diagnosis of AIH [57]