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Vascular Effects Preclinical research suggests BPC-157 may interact with pathways involving: vascular endothelial growth factor (VEGF) nitric-oxiderelated signaling These interactions have been studied in models involving: microvascular injury circulatory impairment induced myocardial injury in rodents Findings are preliminary and may not translate to clinical settings

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Only if using Hooke Kit [Ser 140 ]-PLP 139-151 /CFA Emulsion PTXx2 (EK-0123): 22-26 hours after injection of the emulsion, intraperitoneally inject the second dose of pertussis toxin into the mice