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We found that in cats, the AIM is too tightly bound to the IgM to launch, and as a result, the debris doesnt get cleaned up. 3 When the AIM and IgM dont dissociate (become unattached), the dead cells and debris in the cats system dont get destroyed and cleaned up, which is why, according to Miyazaki, so many cats develop acute kidney injury or other kidney-related diseases

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Fluoro-Jade C (FJC) staining showed neurodegeneration in the hippocampal CA1 and DG regions in mice in the H7d and H14d groups compared with the Con group (Fig