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Front Neurol 13:912647 Basura G, Cienkowski K, Hamlin L, Ray C, Rutherford C, Stamper G, Schooling T, Ambrose J (2023) American speech-language-hearing association clinical practice guideline on aural rehabilitation for adults with hearing loss

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This metabolic defect leads to the accumulation of damaged, depolarized mitochondria that leak chronic levels of mtROS into the cytosol