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doi: 10.1007/s10555-023-10117-y 36 FengJ.GongZ.SunZ.LiJ.XuN.ThorneR

DEFECTS OF FATTY ACID ENTRY INTO MITOCHONDRIA Short- and medium-chain fatty acids can enter mitochondria directly, but fatty acids longer than C 12 must be esterified with coenzyme A and transported across the mitochondrial membrane by carnitine palmitoyltransferases (CPT) I and II, and carnitine-acylcarnitine translocase (see Fig