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10.1016/j.phytochem.2009.12.012 Phytochemistry 21 DubeyS.MisraP.DwivediS.ChatterjeeS.BagS

SAM is a substrate for many chromatin modification enzymes, capable of donating one methyl-group for protein and DNA methylation [94]

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Alemtuzumab therapy, used for depletion of circulating lymphocytes in the therapy of multiple sclerosis is followed by development of GD in a third of such treated patient within 6 months of recovery from T cell depletion (50)

For example, topical application of GHK-Cu (a copper-bound form of GHK) has been clinically investigated for enhancing skin repair, reducing inflammation, and promoting angiogenesis