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Description

Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress

Widmer RJ, Lerman A

K.DrevetJ

Moreover, beyond the role of tumor suppressor protein p53 in apoptosis, autophagy, and cell cycle, emerging evidence suggests that it sensitizes cells to ferroptosis via the regulation of cystine metabolism and ROS responses [15]