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In patients with chronic cerebrovascular insufficiency, treatment with Semax has shown significant clinical improvement, stabilization of disease progression, and a reduction in the risk of stroke and transient ischemic attacks (Gusev et al., Zh Nevrol Psikhiatr 2005)

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Renal function should be watched if protein intake is substantially increased, especially in patients with marginal kidney function, though studies have not shown harm up to 1.5 g/kg protein in elders with normal renal function [127]

These methods include incorporating nanoparticles into the polymer matrix destined for reinforcement in properties such as toughness and strength

and (5) targeted delivery to desired tissues [42, 147,148,149]