hepatic glutathione insulin transhydrogenase Mitochondrial – a key enzyme in secretion and, potentially, diabetes: Trends in Biochemical Sciences Cullin 3 RING E3 ligase
Cullin 3 RING E3 ligase inactivation causes NRF2 dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance PNAS NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress bioRxiv NADPH: Reductive Biosynthesis and Cellular Redox Control The Medical Biochemistry Page Glutathione disulfide sensitizes hepatocytes to TNF mediated cytotoxicity via IKK S glutathionylation: a potential mechanism underlying non alcoholic fatty liver disease Experimental & Molecular Medicine Insulin degradation. XXVIII. Immunocytochemical localization of glutathione insulin transhydrogenase in the pancreas, kidney and liver of normal and streptozotocin diabetic rats and of lean and obese (ob ob) mice Diabetologia Springer Nature Link
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