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Intracellular Fe 2+ exists in the form of a labile iron pool and binds to low molecular weight compounds such as GSH (20)

But it does not cause a direct rise in testosterone levels

Integrating multimorbidity into a whole-body understanding of disease using spatial genomics

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In response to stress, an intricate molecular mechanism facilitated by sensor cysteines within Keap1 allows Nrf2 to escape ubiquitination, accumulate within the cell, and translocate to the nucleus, where it can promote its antioxidant transcription program