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To evaluate mitochondrial function in Peli3 / KO mice, we assessed mitochondrial dehydrogenase activity by the MTT assay

Studies suggest that using a PEG tube at the right time may extend life by 36 months (Guillemin et al., 2022)

The mice were pretreated with dopamine antagonist haloperidol (5.0 mg/kg i.p.) and subsequently treated with amphetamine (20 mg/kg i.p.1, 2, 4 and 10 days after haloperidol pre-treatment), which is usually used for the study of behavioral supersensitivity to an amphetamine stimulating effect

Thus, designing a cancer-targeting strategy in a tumor microenvironment-independent manner is acquisitive, so that it can be applied to a broad range of solid tumors