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Its a cornerstone of many projects within our Mitochondrial Research community

The mechanism of APAP hepatotoxicity is similar in humans and mice [104]

Table 1 summarizes the clinical studies investigating the potential role of different agents in the prevention of peripheral neuropathy (PN) secondary to paclitaxel chemotherapy

Migration scratch assay Thyroid cancer cells (2 10 5 ) were cultured in 24-well plate to 8090% confluency

Although this adaptation initially helps meet the hearts high energy demands, chronic reliance on FA oxidation results in lipotoxicity, mitochondrial stress, and eventually, impaired cardiac function