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conversely, cysteine replenishment restored glutathione synthesis, promoted the clearance of accumulated peroxides, and ultimately alleviated the lethal effects induced by KU-57788 (Fig

We expected that inhibition of ENO activity by POMHEX 25 (which was also suggested in Mullers comments 22 ) would result in the entry of glucose-derived carbon into the glyoxalase pathway and simultaneously block lactate production

Signals were detected by enhanced chemiluminescence solution (GE Healthcare) for visualizing protein expression