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18 DeewatthanawongR.NockJ

IL-4 and IL-10 promotes phagocytic activity of microglia by up-regulation of TREM2

Others require the full escalation to maximum dose before seeing significant results

Ngoi ra, vin ung cn tng cng sc khe h min dch, thi c gan, chng oxy ha v h tr nng cao sc khe tng th

A reasonable bar would be at least one phase 2 RCT in a clinically relevant population (cognitive impairment, mild Alzheimer disease, post-stroke recovery, or similar) showing clinical efficacy with acceptable safety