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3.6.4 Polysaccharides regulate tumor-suppressive and oncogenic miRNA networks Fucoidan exhibits dual miRNA regulation affecting both tumor-suppressive and oncogenic pathways

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Current research focuses on cellular and animal models, while human studies on Se-enriched foods or compounds for AD ferroptosis prevention remain limited and warrant further exploration

The primary methods use epichlorohydrin as the starting material, differing in whether the chemical resolution is performed at different stages of the reaction or a chiral reagent is introduced before the reaction for asymmetric induction to obtain L-carnitine

This azobenzene-based design allowed reverse photoregulation of NAMPT activity and downstream NAD + levels, crucially avoiding the off-target toxicity in the dark state that plagues inhibitor-based PS-PROTACs and thereby laying a foundation for clinical applications