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In summary, shark cartilage-derived peptides may present interesting targets for plaque stabilization that could be used in combination with lipid-lowering therapies in patients with atherosclerosis

J Physiol 558:530 Magistretti PJ (2006) Neuron-glia metabolic coupling and plasticity

However, the Extracorporeal Treatment in Poisoning (EXTRIP) consensus guidelines recommend consideration of hemodialysis for patients with altered mental status, metabolic acidosis, an elevated lactate, and an acetaminophen concentration is greater than 700 mcg/ml even if NAC is administered