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RAS-selective lethal 3 (RSL3) inhibits GPX4 by covalently binding to it, leading to lipid peroxide accumulation and ferroptosis induction

Hyperactive Wnt signaling can lead to aberrant cell proliferation and has been signified in the pathogenesis of BC, CRC, melanoma, and leukemia [94]

Results vary depending on the vitamin used and individual response

Notably, decision tree modeling using the NAC metadata cohort as the training set and the AMC cohort as the validation set showed strong performance when applying the union AMC data-driven classifier, particularly in both the NAC metadata and AMC cohorts (Fig

It is the AEDG peptide associated with acetate or acetic acid