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Deficits in glutathione have been linked to multiple neurodegenerative and neuropsychiatric disorders

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Furthermore, copper can bind directly to key proteins (e.g., prion protein, A, or tau), forming abnormal aggregates that magnify brain tissue injury in a vicious cycle (2)

Ultra-performance liquid chromatography - mass spectrometry (UPLC-MS) The harvested cells were washed twice with cold PBS and fixed in 80% methanol (Fisher Chemical, LC-MS grade) precooled in dry ice

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