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In that sense, glioblastoma cells with high expression of NRF2 could evade cell death induced by TMZ through the GSH-drug efflux by high levels of MRP1, becoming chemoresistant

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To verify Gpx4 overexpression in SOD1 G93A GPX4 mice, we compared levels of Gpx4 protein in spinal cord tissues from SOD1 G93A GPX4 and control SOD1 G93A mice