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Glycinamide, a small -MSH-mimicking peptide blocking MC1R receptor, inhibited melanin synthesis in melanocytes and reduced skin pigmentation in volunteers after topical application [117]

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doi: 10.1021/pr8004309 32 CerquettiM.GiufrM

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This work demonstrates the improved effectiveness of high-dose Vit-C by the use of BC tumor spheroids, consistent with current developments in 3D culture technology