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For example, wild-type p53 replacement therapy, although widely studied and used, is unable to repair or eliminate aberrant genes and is often considered insufficiently effective in clinical practice

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*Correspondence: Chao Liang, [email protected] These authors have contributed equally to this work This article was submitted to Autoimmune and Autoinflammatory Disorders, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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It is also the world's first drug approved for the treatment of adolescent alopecia areata

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Wu MN, Ho K, Crocker A, Yue Z, Koh K, Sehgal A (2009) The effects of caffeine on sleep in Drosophila require PKA activity, but not the adenosine receptor

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BOOSTS IMMUNE HEALTH: Vitamin C is a highly effective antioxidant, due to its ability to donate electrons, thus protecting important biomolecules from damage by oxidants generated by free radicals

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