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Rapamycin reduces seizure frequency in patients with tuberous sclerosis complex by 25% and also reduces the use of AEDs (Zou et al

Poorly managed therapeutic insulin can cause diabetic patients to experience broad fluctuations in glucose concentrations, ranging from hyperglycemic to hypoglycemic states

DNA methylation is usually a repressive mark in the tissue-specific gene silencing and allele-specific inactivation of the X-chromosome, which is associated with hypermethylation of CpG islands (1)

doi: 10.1126/science.1251816 181 GrilloMAMarianiGFerrarisJR

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