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B12 overdose symptoms include skin rashes, itching, upset stomach (nausea, vomiting, diarrhea), b12 overdose headache, and feeling anxious or nervous

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Mense S, Schmit RF

SAM S-adenosyl-L-[methyl-3H] methionine PRMT3 activity assay A radiometric assay was performed by RBC using 100 M-5 nM SAH as an inhibitor positive control