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The inflammatory bowel disease component typically presents before or simultaneously with PSC diagnosis, though some cases emerge afterward

The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

Proteins That Facilitate Granule Priming, Docking, and Fusion Given the role of BDNF in neuronal function, more work has been done to identify the proteins that facilitate the exocytosis of BDNF-containing secretory granules