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In contrast, KD, defined by high-fat, very low-carbohydrate, and moderate protein intake, induces a state of nutritional ketosis with elevated circulating ketone bodies, including -hydroxybutyrate

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In both regions, NSPCs are immersed in a particular microenvironment composed of diverse cellular constituents, such as astrocytes, pericytes, ependymocytes, and vascular and microglial cells (Batiz et al., 2015

This often results in poor texture of the skin and becomes a reason behind the appearance of dryness and roughness, which leads to premature aging

doi: 10.1158/1078-0432.CCR-11-0544 148 HardeeMEMarciscanoAEMedina-RamirezCMZagzagDNarayanaALonningSMet al